US 7,462,642 B2
	Anti-cancer combinations
Liang-Chuan Steve Wang, Auckland (New Zealand); James William Paxton, Auckland (New Zealand); Lai-Ming Ching, Auckland (New Zealand); Bruce Charles Baguley, Auckland (New Zealand); and Philip Kestell, Auckland (New Zealand)
Assigned to Cancer Research Technology Limited, London (United Kingdom)
Filed on Sep. 22, 2004, as Appl. No. 10/946,833.
Application 10/946833 is a continuation in part of application No. PCT/GB03/01320, filed on Mar. 20, 2003.
Prior Publication US 2005/0131059 A1, Jun. 16, 2005
Int. Cl. A61K 31/35 (2006.01)

U.S. Cl. 514—455

6 Claims

1. A method for treating colon cancer, which comprises administering to a mammal in need of treatment an effective amount of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) or a pharmaceutically acceptable salt thereof and concomitantly or sequentially administering an effective amount of diclofenac, wherein said effective amount of said diclofenac is in the range of 0.01 to 5 mg/kg, and wherein the ratio of said DMXAA to said diclofenac is in the range of 150:1 to 1:1.