US 7,593,763 B2
Non-invasive in vivo measurement of macular carotenoids
James L. Lambert, Sunland, Calif. (US); and Mark S. Borchert, La Canada, Calif. (US)
Assigned to Childrens Hospital Los Angeles, Los Angeles, Calif. (US); and California Institute of Technology, Pasadena, Calif. (US)
Filed on Feb. 05, 2004, as Appl. No. 10/773,099.
Claims priority of provisional application 60/445046, filed on Feb. 05, 2003.
Prior Publication US 2004/0260183 A1, Dec. 23, 2004
Int. Cl. A61B 6/00 (2006.01)
U.S. Cl. 600—476  [600/473] 26 Claims
OG exemplary drawing
 
1. A non-invasive in vivo method for assessing carotenoids in the retina and/or macula, comprising:
performing Optical Coherence Tomography (OCT) on a retina of a subject to obtain absorption and/or reflectance spectral data correlated with carotenoid levels; and
generating a spatial representation of carotenoid levels in the retina based on comparing the spectral data from the OCT of the retina with a priori reference spectra.