US 7,572,929 B2
Dithiocarbonate containing macromers and polymers derived therefrom
Ankur S. Kulshrestha, Jersey City, N.J. (US); Kevin Cooper, Flemington, N.J. (US); and Walter R. Laredo, Hillsborough, N.J. (US)
Assigned to Ethicon, Inc. - USA, Somerville, N.J. (US)
Filed on Mar. 27, 2006, as Appl. No. 11/390,124.
Prior Publication US 2007/0225460 A1, Sep. 27, 2007
Int. Cl. C07C 329/18 (2006.01); C08F 28/06 (2006.01)
U.S. Cl. 558—247  [558/245; 536/122; 508/445] 9 Claims
 
1. A dithiocarbonate-containing macromer having the formula:

OG Complex Work Unit Drawing
wherein n is an integer greater than or equal to two;
R1 is selected from the group consisting of an alpha-, omega-diol containing from C-2 to C-22 carbon atoms; an alpha-, omega-diol containing ether linkages; and a polyol; and
R2 is a biodegradable or water-soluble linkage selected from the group consisting of an ester, an amide, a carbonate, an ester-amide, an orthoester, an anhydride, an imine, a phosphazene, a poly(peptide), a poly(hydroxy acid), a poly(orthocarbonate), a poly(anhydride), a poly(lactone), a poly(aminoacid), a poly(carbonate), poly(phosphonate), a poly(oxaester), a poly(alkylene diglycolate), a fatty acid polyester, a poly(ester-amide), a polydepsipeptide, a poly(orthoester), poly(phosphazene), poly(ethylene glycol), poly(ethylene oxide), poly(vinyl alcohol), poly(ethylene-co-vinyl alcohol), poly(acrylic acid), poly(ethylene-co-acrylic acid), poly(ethyloxazoline), polyvinylpyrrolidone, poly(ethylene-co-vinyl pyrrolidone), poly(maleic acid), poly(ethylene-co-maleic acid), poly(acrylamide), poly(ethylenimine), poly(ethylene oxide)-co-poly(propylene oxide) block copolymers, and combinations thereof; and
R3 is selected from the group consisting of hydrogen, methyl, ethyl, and propyl.