| US 7,572,252 B1 | ||
| Electrotransport agent delivery method and apparatus | ||
| J. Bradley Phipps, Plymouth, Minn. (US); Gary A. Lattin, Forest Lake, Minn. (US); Ronald P. Haak, Menlo Park, Calif. (US); Suneel Gupta, Redwood City, Calif. (US); and Felix Theeuwes, Los Altos Hills, Calif. (US) | ||
| Assigned to Alza Corporation, Mountain View, Calif. (US) | ||
| Filed on Jun. 07, 1995, as Appl. No. 8/484,934. | ||
| Int. Cl. A61M 31/00 (2006.01) | ||
| U.S. Cl. 604—501 | 2 Claims |

| 1. A method of increasing the delivery efficiency of an agent delivered through a body surface by electrotransport, the delivery efficiency being equal to the rate of agent delivery through the body surface per unit of applied electric current, comprising delivering the agent by electrotransport through the body surface by applying current having a density of about 240 μA/cm2 for about 2.5 minutes every 15 minutes for 1 hour to transform the body surface to an enhanced, non-transitory agent delivery efficiency state, and then applying current having a density of about 20 μA/cm2. |