| US 7,476,753 B2 | ||
| 3-aryl-2-cyano-3-hydroxy-acrylic acid derivatives | ||
| Dinesh Narendra Rele, Mumbai (India); Harjinder Singh Bhatti, Navi Mumbai (India); Werner Hölzl, Eschentzwiller (France); Sophie Marquais-Bienewald, Hegenheim (France); Errol Vincent Mathias, Mumbai (India); Andrea Preuss, Basel (Switzerland); and Barbara Wagner, Lörrach (Germany) | ||
| Assigned to Ciba Specialty Chemicals Corporation, Tarrytown, N.Y. (US) | ||
| Appl. No. 10/565,789 PCT Filed Jul. 19, 2004, PCT No. PCT/EP2004/051533 § 371(c)(1), (2), (4) Date Jan. 25, 2006, PCT Pub. No. WO2005/012235, PCT Pub. Date Feb. 10, 2005. |
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| Claims priority of application No. 03102324 (EP), filed on Jul. 29, 2003. | ||
| Prior Publication US 2006/0228965 A1, Oct. 12, 2006 | ||
| Int. Cl. C07C 255/07 (2006.01); A61K 8/34 (2006.01) | ||
| U.S. Cl. 558—401 [424/401] | 8 Claims |
1. Compounds of formula
 R1 is C6-C10aryl; or a group of formula (1a1)
 R2 is hydrogen; or C1-C20alkyl.
|